Human IL-20 R alpha Protein

• Catalog Number: orb1184776
• Category: Proteins
• Description: IL-20 R alpha (Interleukin-20 receptor subunit alpha) forms a functional heterodimer with the IL-20 beta subunit, and transduces ligand-binding at least in part through STAT3 activation. The IL-20 subfamily of cytokines and receptors are members of the larger IL-10 family, which are grouped together based on their utilization of common receptor subunits, similarities in their target-cell profiles, and biological functions. This subfamily consists of the cytokines, IL-19, IL-20, IL-22, IL-24, and IL-26, as well as the receptors, IL-20RA, IL-20RB, IL-10RB, and IL-22RA1.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 27.1 kDa
• Target: IL-20 R alpha
• Source: Human IL-20 R alpha Protein, His Tag (orb1184776) is expressed from human 293 cells (HEK293). It contains AA Val 30 - Lys 250 (Accession # Q9UHF4-1).
• Expression System: HEK293
• Biological Activity: Human IL-20, His Tagimmobilized on CM5 Chip can bind Human IL-20 R alpha Protein, His Tag with an affinity constant of 3.31 μM as determined in a SPR assay (Biacore 8K) (QC tested).
• Expression Region: Val 30 - Lys 250
• Endotoxins: 1.0 EU per μg
• NCBI: NP_055247.3
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: Interleukin-20 receptor subunit alpha,IL-20 recept
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 27.1 kDa. The protein migrates as 35-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Human IL-20, His Tag (Cat. No. orb1146995) immobilized on CM5 Chip can bind Human IL-20 R alpha Protein, His Tag (Cat. No. orb1184776) with an affinity constant of 3.31 μM as determined in a SPR assay (Biacore 8K) (QC tested).