Human IL-17 RB Protein

• Catalog Number: orb1496253
• Category: Proteins
• Description: IL17RB (EVI27, IL17Rh1) is a single pass transmembrane receptor which belongs to IL17R family of cytokine receptors. It was found to be expressed in liver, brain, testis and lungs. The ligand for IL17RB is IL17E, also known as IL25. The five IL-17 receptors (IL17RA-IL17RE) exhibit considerable sequence divergence between one another, but all appear to contain extracellular domains composed of fibronectin type-III (FnIII) domains, and cytoplasmic SEF/IL-17R (SEFIR) domains that show loose homology to Toll/IL-1R (TLR) domains.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 56.7 kDa
• Target: IL-17 RB
• Source: Human IL-17 RB, Fc Tag (orb1496253) is expressed from human 293 cells (HEK293). It contains AA Arg 18 - Pro 292 (Accession # Q9NRM6-1 (EVI27) & Q9NRM6-1(IL17Rh1)).
• Expression System: HEK293
• Expression Region: Arg 18 - Pro 292
• Endotoxins: 1.0 EU per μg
• NCBI: NP_061195.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: 50 mM Tris,100 mM Glycine,25 mM Arginine,150 mM NaCl,pH7.5
• Alternative names: IL-17 RB,Interleukin-17 receptor B,Interleukin-17
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.7 kDa. The protein migrates as 65-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.