Human IL-1 Rrp2 / IL-1 R6 Protein

• Catalog Number: orb511252
• Category: Proteins
• Description: The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 37.8 kDa
• Target: IL-1 Rrp2
• Source: Human IL-1 Rrp2, His Tag (orb511252) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 335 (Accession # Q9HB29-1).
• Expression System: HEK293
• Biological Activity: Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2, His Tag with a linear range of 0.008-0.5 μg/mL (QC tested).
• Expression Region: Asp 20 - Arg 335
• Endotoxins: 1.0 EU per μg
• NCBI: NP_003845.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: IL-1 R6,IL-1 Rrp2,IL1RL2,IL-1RL2,IL1Rrp2,IL-1Rrp2,
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.8 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2, His Tag (Cat. No. orb511252) with a linear range of 0.008-0.5 μg/mL (QC tested).