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Catalog Number | orb750338 |
---|---|
Category | Proteins |
Description | The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). All family members possess three immunoglobulin (Ig)-like domains in their extracellular region. Most members also have an intracellular TIR (Toll-like receptor/IL-1 receptor signaling) domain that is also conserved in the Toll-like receptor family. Related proteins, SIGIRR (single Ig domain-containing IL-1 R-related molecule) and IL-18BP, differ from the other members by having only one Ig domain. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 37.9 kDa |
Target | IL-1 Rrp2 |
Source | Human IL-1 Rrp2 (C154S, C262S) Protein, His Tag (orb750338) is expressed from human 293 cells (HEK293). It contains AA Asp 20 - Arg 335 (Accession # Q9HB29-1 (C154S, C262S)). |
Expression System | HEK293 |
Biological Activity | Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2 (C154S, C262S) Protein, His Tag with a linear range of 4-125 ng/mL (QC tested). |
Expression Region | Asp 20 - Arg 335 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_003845.2 |
Storage | -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | IL-1 R6,IL-1 Rrp2,IL1RL2,IL-1RL2,IL1Rrp2,IL-1Rrp2, Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.9 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
Immobilized Anti-IL36R Antibody, Human IgG1 at 1 μg/mL (100 μL/well) can bind Human IL-1 Rrp2 (C154S, C262S) Protein, His Tag (Cat. No. orb750338) with a linear range of 4-125 ng/mL (QC tested).
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