Human Iba1 / AIF-1 Protein

• Catalog Number: orb636715
• Category: Proteins
• Description: Allograft inflammatory factor 1 (AIF1), also known as IBA1, daintain and Protein G1, is an actin-binding protein. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 18.6 kDa
• Target: Iba1
• Source: Human Iba1, His Tag (orb636715) is expressed from E. coli cells. It contains AA Met 1 - Pro 147 (Accession # P55008-1).
• Expression System: E. coli
• Expression Region: Met 1 - Pro 147
• Endotoxins: 1.0 EU per μg
• NCBI: NP_001614.3
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: Iba1,AIF-1,AIF1,G1,IBA1,LCP1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.6 kDa. The protein migrates as 18-20 kDa under reducing (R) condition (SDS-PAGE).
• Expiration Date: 6 months from date of receipt.