Human HE4 / WFDC2 Protein

Catalog Number: orb257543

Catalog Number	orb257543
Category	Proteins
Description	Human Epididymis Protein 4 (HE4) is also known as WAP four-disulfide core domain protein 2 (WFDC2), Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, is a member of the WFDC domain family. HE4 / WFDC2 is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. HE4 is also a small secretory protein, which may be involved in sperm maturation.
Reactivity	Human
Tag	C-6×His
Form/Appearance	Powder
Purity	95%
Conjugation	Unconjugated
MW	10.9 kDa
Target	HE4
Protein Sequence	AAH46106
Source	Human HE4, His Tag (orb257543) is expressed from human 293 cells (HEK293). It contains AA Glu 31 - Phe 124 (Accession # AAH46106).
Expression System	HEK293
Expression Region	Glu 31 - Phe 124
Endotoxins	1.0 EU per μg
NCBI	AAH46106
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	HE4,WAP5,WFDC2,EDDM4 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.9 kDa. The protein migrates as 19-23 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human HE4 protein

Purity:	≥90% as determined by SDS-PAGE
Source:	This protein contains the human WFDC2(Met1-Phe124) was fused with the C-terminal His Tag and expressed in Mammalian cells.