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Catalog Number | orb257515 |
---|---|
Category | Proteins |
Description | Glycoprotein A33 (GPA33) is also known as Cell surface A33 antigen, is a single-pass type I membrane protein which is expressed in normal gastrointestinal epithelium and in 95% of colon cancers. GPA33 The predicted mature protein has a 213-amino acid extracellular region, a single transmembrane domain, and a 62-amino acid intracellular tail. The sequence of the extracellular region contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain characteristic of the CD2 subgroup of the immunoglobulin (Ig) superfamily, which contains. GPA33 may play a role in cell-cell recognition and signaling. |
Reactivity | Human |
Tag | C-6×His |
Form/Appearance | Powder |
Purity | 96% |
Conjugation | Unconjugated |
MW | 24.4 kDa |
Target | GPA33 |
Protein Sequence | AAH74830 |
Source | Human GPA33, His Tag (orb257515) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Val 235 (Accession # AAH74830). |
Expression System | HEK293 |
Expression Region | Ile 22 - Val 235 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH74830 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | GPA33,A33 Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.4 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human GPA33 protein
Unconjugated | |
95% | |
50.1 kDa | |
Human GPA33, Fc Tag (orb867335) is expressed from human 293 cells (HEK293). It contains AA Ile 22 - Val 235 (Accession # Q99795-1). |
> 95% by Tris-Bis PAGE, > 95% by SEC-HPLC | |
KMP2068, Biotinylated Recombinant Human GPA33 / A33 Protein is produced by Expi293 expression system. The target protein is expressed with sequence (Ile22-Val235) of Human GPA33 / A33 fused with His Tag and Avi tag at the C-terminal. |
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