Human Glutaredoxin 1 / GLRX1 Protein

• Catalog Number: orb257509
• Category: Proteins
• Description: Glutaredoxin-1 (GRX1) is also known as Thioltransferase-1 (TTase-1), GLRX, GRX, GLRX1, which belongs to the glutaredoxin family. GRX1 / GLRX contains one glutaredoxin domain, which exists in either a reduced or an oxidized form. GRX1 / GLRX has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase and functions as electron carriers in the glutathione-dependent synthesis of deoxyribonucleotides by the enzymeribonucleotide reductase.
• Reactivity: Human
• Tag: N-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 12.7 kDa
• Target: Glutaredoxin 1
• Source: Human Glutaredoxin 1, His Tag (orb257509) is expressed from E. coli cells. It contains AA Met 1 - Gln 106 (Accession # NP_001112362).
• Expression System: E. coli
• Expression Region: Met 1 - Gln 106
• Endotoxins: 1.0 EU per μg
• NCBI: NP_001112362
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: 50 mM Tris, 150 mM NaCl, pH7.5 with 1 mM DTT
• Alternative names: GLRX,GRX,TTase-1,GLRX1,GRX1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 12.7 kDa. The protein migrates as 12 kDa under reducing (R) condition (SDS-PAGE).
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human Glutaredoxin 1 protein