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Catalog Number | orb402834 |
---|---|
Category | Proteins |
Description | Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer. |
Reactivity | Human |
Tag | N-9×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 38.1 kDa |
Target | Galectin-4 |
Protein Sequence | NP_006140.1 |
Source | Human Galectin-4, His Tag (orb402834) is expressed from human 293 cells (HEK293). It contains AA Met 1 - Ile 323 (Accession # P56470-1). |
Expression System | HEK293 |
Expression Region | Met 1 - Ile 323 |
Endotoxins | 1.0 EU per μg |
NCBI | NP_006140.1 |
Storage | -20℃ |
Buffer/Preservatives | 50 mM HEPES, 150 mM NaCl, 5 mM EDTA, 2 mM TCEP, pH7.4 |
Alternative names | LGALS4,L36LBP,Gal-4,Antigen NY-CO-27,Lactose-bindi Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 38.1 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
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