Human Follistatin-like 1 / FSTL1 Protein

• Catalog Number: orb257484
• Category: Proteins
• Description: Follistatin-related protein 1 (FSTL1) is also known as Follistatin-like protein 1 (FRP). FSTL1 is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain and one VWFC domain. FSTL1 is overexpressed in synovial tissues from rheumatoid arthritis. Follistatin-like protein 1 / FSTL1 may modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 binds heparin.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 33.8 kDa
• Target: Follistatin-like 1
• Source: Human Follistatin-like 1, His Tag (orb257484) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Ile 308 (Accession # AAH00055).
• Expression System: HEK293
• Expression Region: Glu 21 - Ile 308
• Endotoxins: 1.0 EU per μg
• NCBI: AAH00055
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: FSTL1,FRP,FSL1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.8 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to different glycosylation.
• Expiration Date: 6 months from date of receipt.

References

Dong, Yingying et al. Blocking follistatin-like 1 attenuates bleomycin-induced pulmonary fibrosis in mice J Exp Med, 212, 235-252 (2015)

PubMed: 25584011

SDS-PAGE analysis of Human Follistatin-like 1 protein