Human FGF-10 / KGF 2 Protein

• Catalog Number: orb1496146
• Category: Proteins
• Description: Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22). As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.
• Reactivity: Human
• Tag: N-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 21.2 kDa
• Target: FGF-10
• Protein Sequence: Gln 38 - Ser 208
• Source: Human FGF-10, His Tag (orb1496146) is expressed from E. coli cells. It contains AA Gln 38 - Ser 208 (Accession # O15520-1).
• Expression System: E. coli
• Expression Region: Gln 38 - Ser 208
• Endotoxins: 0.1 EU per μg
• Storage: -20℃
• Buffer/Preservatives: 20 mM Mops,0.2 M Arginine,1 mM EDTA,1 mM DTT,pH7.0
• Alternative names: FGF-10,Fibroblast growth factor 10,Keratinocyte gr
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.2 kDa. The protein migrates as 27 kDa under reducing (R) condition (SDS-PAGE).
• Expiration Date: 6 months from date of receipt.