Human Fc Protein

Catalog Number: orb257462

Catalog Number	orb257462
Category	Proteins
Description	Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). IgG1 Fc was reported has a novel role as a potential anti-inflammatory drug for treatment of human autoimmune diseases.
Reactivity	Human
Tag	Native
Form/Appearance	Powder
Purity	95%
Conjugation	Unconjugated
MW	26.1 kDa
Target	IgG1 Fc
Protein Sequence	Glu 99 - Lys 330
Source	Human IgG Fc, Tag Free (orb257462) is expressed from human 293 cells (HEK293). It contains AA Glu 99 - Lys 330 (Accession # P01857-1).
Expression System	HEK293
Expression Region	Glu 99 - Lys 330
Endotoxins	1.0 EU per μg
Storage	-20℃
Buffer/Preservatives	Tris with Glycine, Arginine and NaCl, pH7.5
Alternative names	IgG1 Read more...
Note	For research use only
Application notes	This protein carries no "tag". The protein has a calculated MW of 26.1 kDa. The protein migrates as 32-34 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human IgG Fc protein

Item 1 of 7
Human ACE2/ACEH Protein. Fc Tag [orb1945965]
Applications:
ELISA
Sizes Available: 200 μl, 20 μl
Item 1 of 2
Human Complement C5a Protein [orb257232]
Conjugation:
Unconjugated
Purity:
95%
MW:
8.3 kDa
Source:
Human Complement C5a, Tag Free (orb257232) is expressed from E. coli cells. It contains AA Leu 679 - Arg 751 (Accession # P01031).
Sizes Available: 1 mg, 50 μg
Item 1 of 1
Mouse Complement C5a Protein [orb570259]
Conjugation:
Unconjugated
Purity:
95%
MW:
10.9 kDa
Source:
Mouse Complement C5a, His Tag (orb570259) is expressed from E. coli cells. It contains AA Asn 679 - Arg 755 (Accession # P06684).
Sizes Available: 100 μg, 1 mg
Item 1 of 1
Cynomolgus Complement C5a Protein [orb570258]
Conjugation:
Unconjugated
Purity:
95%
MW:
8.4 kDa
Source:
Cynomolgus Complement C5a, Tag Free (orb570258) is expressed from E. coli cells. It contains AA Met 678 - Arg 751 (Accession # XP_015292262.1).
Sizes Available: 100 μg, 1 mg
Item 1 of 1
Cynomolgus Complement C5a Protein [orb1496181]
Conjugation:
Unconjugated
Purity:
95%
MW:
10.5 kDa
Source:
Cynomolgus Complement C5a, His Tag (orb1496181) is expressed from E. coli cells. It contains AA Met 678 - Arg 751 (Accession # XP_015292262.2).
Sizes Available: 1 mg, 50 μg

Conjugation:	Unconjugated
Purity:	95%
MW:	8.3 kDa
Source:	Human Complement C5a, Tag Free (orb257232) is expressed from E. coli cells. It contains AA Leu 679 - Arg 751 (Accession # P01031).