Human EGF R Protein

• Catalog Number: orb511277
• Category: Proteins
• Description: The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF-family) of extracellular protein ligands. The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 70.5kDa
• Target: EGF R
• Protein Sequence: NP_005219.2
• Source: Human EGF R, His Tag, low endotoxin (orb511277) is expressed from human 293 cells (HEK293). It contains AA Leu 25 - Ser 645 (Accession # P00533-1).
• Expression System: HEK293
• Expression Region: Leu 25 - Ser 645
• Endotoxins: 0.01 EU per μg
• NCBI: NP_005219.2
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: EGFR,ERBB,ERBB1,HER1,PIG61,mENA
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 70.5kDa. The protein migrates as 77-104 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.