Human DLL4 Protein

• Catalog Number: orb257399
• Category: Proteins
• Description: Delta-like protein 4 (DLL4) is also known as Drosophila Delta homolog 4 (Delta4), which contains one DSL domain and eight EGF-like domains. DLL4 is expressed in vascular endothelium. DLL4 is involved in the Notch signaling pathway as Notch ligand, which can activates NOTCH1 and NOTCH4. DLL4 is involved in angiogenesis and negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. DLL4 can bind to Notch-1 and Notch-4.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 56.2 kDa
• Target: DLL4
• Protein Sequence: AAI06951
• Source: Human DLL4, His Tag (orb257399) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Pro 524 (Accession # Q9NR61-1).
• Expression System: HEK293
• Expression Region: Ser 27 - Pro 524
• Endotoxins: 1.0 EU per μg
• NCBI: AAI06951
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: DLL4,Delta4
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 56.2 kDa. The protein migrates as 55-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human DLL4 protein