Human DLL1 / Delta1 Protein

Catalog Number: orb257943

Catalog Number	orb257943
Category	Proteins
Description	Delta-like protein 1 (DLL1) is also known as Drosophila Delta homolog 1 (Delta1 or H-Delta-1), which contains one DSL domain and eight EGF-like domains. DLL1 is ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation. As for expression, DLL1 is expressed in heart and pancreas, with lower expression in brain and muscle and almost no expression in placenta, lung, liver and kidney. Furthermore, DLL1 acts as a ligand for Notch receptors. Also, DLL1 can block the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor.
Reactivity	Human
Tag	C-10×His
Form/Appearance	Powder
Purity	95%
Conjugation	Unconjugated
MW	58.4 kDa
Target	DLL1
Protein Sequence	NP_005609
Source	Human DLL1, His Tag (orb257943) is expressed from human 293 cells (HEK293). It contains AA Gln 18 - Gly 540 (Accession # NP_005609).
Expression System	HEK293
Expression Region	Gln 18 - Gly 540
Endotoxins	1.0 EU per μg
NCBI	NP_005609
Storage	-20℃
Buffer/Preservatives	50 mM Tris, 150 mM NaCl, pH 7.5
Alternative names	DLL1,Delta1,H-Delta-1 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 58.4 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human DLL1 protein