Human CTGF / CCN2 Protein, Tag Free [Out of stock]

• Catalog Number: orb1821763
• Category: Proteins
• Description: Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
• Reactivity: Human
• Tag: Native
• Form/Appearance: Liquid
• Purity: 95%
• Conjugation: Unconjugated
• MW: 11.2 kDa
• Target: CTGF
• Source: Human CTGF Protein, Tag Free is expressed from E. coli cells. It contains AA Gly 253 - Ala 349 (Accession # Q5M8T4-1 ).
• Expression System: E. coli
• Expression Region: Gly 253 - Ala 349
• Endotoxins: 0.1 EU per μg
• Storage: The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
• Buffer/Preservatives: PBS, pH 7.4
• Note: For research use only
• Application notes: This protein carries no "tag". The protein has a calculated MW of 11.2 kDa. The protein migrates as 10-11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
• Expiration Date: 6 months from date of receipt.