Human Coagulation factor IX / F9 Protein, His Tag (active enzyme, MALS verified)

• Catalog Number: orb1499257
• Category: Proteins
• Description: Coagulation factor VII is also known as F7, SPCA and Proconvertin. Heterodimer of a light chain and a heavy chain linked by a disulfide bond. Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 50.6 kDa
• Target: Coagulation factor IX
• Protein Sequence: Thr 29 - Thr 461
• Source: Human Coagulation factor IX Protein, His Tag (orb1499257) is expressed from human 293 cells (HEK293). It contains AA Thr 29 - Thr 461 (Accession # P00740-1).
• Expression System: HEK293
• Expression Region: Thr 29 - Thr 461
• Endotoxins: 1.0 EU per μg
• Storage: RT
• Buffer/Preservatives: 50 mM Tris,150 mM NaCl,pH8.0
• Alternative names: Coagulation factor Ix,PTC,F9,THPH8,FIX,Plasma Thro
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 50.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.