Human CEACAM-1 / CD66a Protein

• Catalog Number: orb257335
• Category: Proteins
• Description: Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 92%
• Conjugation: Unconjugated
• MW: 44.1 kDa
• Target: CEACAM-1
• Protein Sequence: AAH14473
• Source: Human CEACAM-1, His Tag (orb257335) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 428 (Accession # AAH14473).
• Expression System: HEK293
• Expression Region: Gln 35 - Gly 428
• Endotoxins: 1.0 EU per μg
• NCBI: AAH14473
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: CEACAM1,CD66a,BGP,BGP1,BGPI
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.1 kDa. The protein migrates as 57-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to different glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human CEACAM-1 protein