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Catalog Number | orb257335 |
---|---|
Category | Proteins |
Description | Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) is also known as Biliary glycoprotein 1 (BGP1), CD66a, which belongs to the immunoglobulin superfamily or CEA family. CEACAM1 /CD66a contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CEACAM1 /CD66a was described as an adhesion molecule mediating cell adhesion via both homophilic and heterophilic manners, and was detected on leukocytes, epithelia, and endothelia. Studies have revealed that CEACAM1 / BGP-1 performs actions in multiple cellular processes including tissue differentiation, angiogenesis, apoptosis, metastasis, as well as the modulation of innate and adaptive immune responses. |
Reactivity | Human |
Tag | C-6×His |
Form/Appearance | Powder |
Purity | 92% |
Conjugation | Unconjugated |
MW | 44.1 kDa |
Target | CEACAM-1 |
Protein Sequence | AAH14473 |
Source | Human CEACAM-1, His Tag (orb257335) is expressed from human 293 cells (HEK293). It contains AA Gln 35 - Gly 428 (Accession # AAH14473). |
Expression System | HEK293 |
Expression Region | Gln 35 - Gly 428 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH14473 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | CEACAM1,CD66a,BGP,BGP1,BGPI Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.1 kDa. The protein migrates as 57-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to different glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human CEACAM-1 protein
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