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Catalog Number | orb612138 |
---|---|
Category | Proteins |
Description | CD94(Natural killer cells antigen CD94) is also known as KLRD1, KP43, NK cell receptor, Killer cell lectin-like receptor subfamily D member 1. CD94 plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. CD94 pairs with the NKG2 molecule as a heterodimer. The CD94/NKG2 complex, on the surface of natural killer cells interacts with Human Leukocyte Antigen (HLA)-E on target cells. |
Reactivity | Human |
Tag | C-10×His |
Form/Appearance | Powder |
Purity | 90% |
Conjugation | Unconjugated |
MW | 19.1 kDa |
Target | CD94 |
Protein Sequence | Lys 32 - Ile 179 |
Source | Human CD94, His Tag (orb612138) is expressed from human 293 cells (HEK293). It contains AA Lys 32 - Ile 179 (Accession # Q13241-1). |
Expression System | HEK293 |
Expression Region | Lys 32 - Ile 179 |
Endotoxins | 1.0 EU per μg |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | CD94,KLRD1,KP43,NK cell receptor Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.1 kDa. The protein migrates as 24-30 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
ELISA, MS, SDS-PAGE, WB | |
Greater than 95% as determined by reducing SDS-PAGE. | |
Human cells |
ELISA, MS, SDS-PAGE, WB | |
Greater than 95% as determined by reducing SDS-PAGE. | |
Human cells |
Unconjugated | |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 43.3 kDa after removal of the signal peptide.The apparent molecular mass of hFc-CD94 is approximately 55-70 kDa due to glycosylation. | |
Mammalian |
Unconjugated | |
95% | |
44.0 kDa | |
Human CD94, Mouse IgG2a Fc Tag (orb613655) is expressed from human 293 cells (HEK293). It contains AA Lys 32 - Ile 179 (Accession # Q13241-1). |
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