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Catalog Number | orb257297 |
---|---|
Category | Proteins |
Description | Leukocyte antigen CD37 (CD37) is also known as Tetraspanin-26 (Tspan-26) and TSPAN26,which is a member of the transmembrane 4 superfamily or tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins encoded by CD37 gene mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD37 is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. CD37 may play a role in T-cell-B-cell interactions. |
Reactivity | Human |
Tag | N-Fc |
Form/Appearance | Powder |
Purity | 90% |
Conjugation | Unconjugated |
MW | 41.6 kDa |
Target | CD37 |
Protein Sequence | AAI06753 |
Source | Human CD37, Fc Tag (orb257297) is expressed from human 293 cells (HEK293). It contains AA Ala 113 - Asn 240 (Accession # AAI06753). |
Expression System | HEK293 |
Expression Region | Ala 113 - Asn 240 |
Endotoxins | 1.0 EU per μg |
NCBI | AAI06753 |
Storage | -20℃ |
Buffer/Preservatives | Tris with Glycine, Arginine and NaCl, pH7.5 |
Alternative names | CD37,Tspan-26,TSPAN26 Read more... |
Note | For research use only |
Application notes | This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 41.6 kDa. The protein migrates as 45-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human CD37 protein
Greater than 85% as determined by SDS-PAGE. | |
34.5 kDa | |
in vitro E.coli expression system |
Unconjugated | |
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. | |
The protein has a predicted molecular mass of 41.0 kDa after removal of the signal peptide.The apparent molecular mass of CD37-hFc is approximately 35-55 kDa due to glycosylation. | |
Mammalian |
The human full length CD37 protein has a MW of 31.7 kDa | |
Mammalian |
Unconjugated | |
95% | |
41.3 kDa | |
Human CD37, Fc Tag (orb762445) is expressed from human 293 cells (HEK293). It contains AA Arg 112 - Asn 241 (Accession # P11049-1). |
Unconjugated | |
90% | |
16.9 kDa | |
Human CD37, His Tag (orb1147005) is expressed from human 293 cells (HEK293). It contains AA Arg 112 - Asn 241 (Accession # P11049-1). |
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