Human CD300c / LMIR2 Protein

• Catalog Number: orb257316
• Category: Proteins
• Description: CMRF35-like molecule 6 (CLM-6) is also known as CD300 antigen-like family member C, CMRF35-A1, Immunoglobulin superfamily member 16 (IgSF16) , CD antigen CD300c, which belongs to the CD300 family. CLM-6 contains one Ig-like V-type (immunoglobulin-like) domain. CD300a/c RNA and surface expression were downregulated after stimulation of plasmacytoid dendritic cells (pDCs) with TLR7 and TLR9 ligands. Exogenous interferon (IFN)-alpha down-regulated CD300a/c expression. CD300a and CD300c play an important role in the cross-regulation of TNF-alpha and IFN-alpha secretion from pDCs. CD300a and CD300c are indistinguishable on the surface of NK cells.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 18.67 kDa
• Target: CD300c
• Protein Sequence: AAH22279
• Source: Human CD300c, His Tag (orb257316) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Arg 183 (Accession # AAH22279).
• Expression System: HEK293
• Expression Region: Gly 21 - Arg 183
• Endotoxins: 1.0 EU per μg
• NCBI: AAH22279
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: CD300C,CLM-6,CMRF35-A1,CMRF-35,CMRF35A,IGSF16
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 18.67 kDa. The protein migrates as 26-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human CD300c protein