Human CD28H / IGPR-1 Protein

• Catalog Number: orb570263
• Category: Proteins
• Description: CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 15.9 kDa
• Target: CD28H
• Protein Sequence: AAH15655
• Source: Human CD28H, His Tag (orb570263) is expressed from human 293 cells (HEK293). It contains AA Leu 23 - Gly 150 (Accession # Q96BF3-1).
• Expression System: HEK293
• Expression Region: Leu 23 - Gly 150
• Endotoxins: 1.0 EU per μg
• NCBI: AAH15655
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: TMIGD2,IGPR1
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 15.9 kDa. The protein migrates as 22-32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.