Human CD27 / TNFRSF7 Protein

Catalog Number: orb257294

Catalog Number	orb257294
Category	Proteins
Description	CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Reactivity	Human
Tag	C-Fc
Form/Appearance	Powder
Purity	95%
Conjugation	Unconjugated
MW	45.9 kDa
Target	CD27
Protein Sequence	NP_001233
Source	Human CD27, Fc Tag (orb257294) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # NP_001233).
Expression System	HEK293
Expression Region	Thr 21 - Ile 192
Endotoxins	1.0 EU per μg
NCBI	NP_001233
Storage	-20℃
Buffer/Preservatives	50 mM Tris, 100 mM Glycine, pH7.5
Alternative names	CD27,TNFRSF7,S152,T14,Tp55 Read more...
Note	For research use only
Application notes	This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 53-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human CD27 protein

Conjugation:	Unconjugated
Purity:	95%
MW:	46.2 kDa
Source:	Human CD27 Protein, Mouse IgG2a Fc Tag (orb511316) is expressed from human 293 cells (HEK293). It contains AA Thr 21 - Ile 192 (Accession # P26842-1).

Sizes Available: 100 μg, 1 mg

Purity:	> 95% by SDS-PAGE.
Source:	KMP1492, Recombinant Human CD27/TNFRSF7 Protein is produced by Human Cell expression system. The target protein is expressed with sequence (Thr21-Ile192) of human CD27/TNFRSF7 (Accession #P26842) fused with an Fc, 6×His Tag at the C-terminus.

Sizes Available: 50 μg, 500 μg