Human CD163 Protein

Catalog Number: orb334885

Catalog Number	orb334885
Category	Proteins
Description	Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
Reactivity	Human
Tag	C-10×His
Form/Appearance	Powder
Purity	95%
Conjugation	Unconjugated
MW	110.4 kDa
Target	CD163
Protein Sequence	Q86VB7
Source	Human CD163, His Tag (orb334885) is expressed from human 293 cells (HEK293). It contains AA Ser 42 - Ser 1045 (Accession # Q86VB7).
Expression System	HEK293
Expression Region	Ser 42 - Ser 1045
Endotoxins	1.0 EU per μg
NCBI	Q86VB7
Storage	-20℃
Buffer/Preservatives	PBS, pH7.4
Alternative names	CD163,M130 Read more...
Note	For research use only
Application notes	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 110.4 kDa. The protein migrates as 135-140 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Expiration Date	6 months from date of receipt.

SDS-PAGE analysis of Human CD163 protein

Conjugation:	Unconjugated
Purity:	The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
MW:	The protein has a predicted molecular mass of 109.5 kDa after removal of the signal peptide. The apparent molecular mass of CD163-His is approximately 130-250 kDa due to glycosylation.
Source:	Mammalian

Sizes Available: 100 μg, 50 μg, 10 μg

Purity:	Greater than 85% as determined by SDS-PAGE.
MW:	54.1 kDa
Source:	E.coli