Human CCL7 / MCP-3 Protein

• Catalog Number: orb1149286
• Category: Proteins
• Description: CCL7, also known as monocyte chemotactic protein-3 (MCP-3), is a CC (cysteine–cysteine) chemokine that is 11–18 kDa in size depending on the level of glycosylation. Its gene has been mapped to chromosome 17q11.2-q12 and is expressed in response to endogenous cytokines or exogenous bacterial products. This protein shares 60–71% homology with MCP-1 and MCP-2 chemokines and consequently binds similar receptors. Receptors CCR1, CCR2, CCR3, and CCR5 have been identified to bind CCL7 in both progenitor and immune cells.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 10.8 kDa
• Target: CCL7
• Source: Human CCL7, His Tag (orb1149286) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Leu 99 (Accession # P80098-1).
• Expression System: HEK293
• Expression Region: Gln 24 - Leu 99
• Endotoxins: 1.0 EU per μg
• NCBI: NP_006264.2
• Storage: -20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: C-C motif chemokine 7,Monocyte chemoattractant pro
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 10.8 kDa. The protein migrates as 14 kDa and 18-20 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.