Human BMPR-1A / ALK-3 Protein

• Catalog Number: orb257183
• Category: Proteins
• Description: The bone morphogenetic protein receptor, type IA is also known as BMPR1A or ALK3 is a protein which in humans is encoded by the BMPR1A gene. BMPR1A has also been designated as CD292 (cluster of differentiation 290). The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A (this protein) and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. Alk3-mediated BMP signaling in AV endocardial/mesenchymal cells plays a central role during cushion morphogenesis.
• Reactivity: Human
• Tag: C-Fc
• Form/Appearance: Powder
• Purity: 98%
• Conjugation: Unconjugated
• MW: 40.3 kDa
• Target: BMPR-1A
• Protein Sequence: CAA80257
• Source: Human BMPR-1A, Fc Tag (orb257183) is expressed from human 293 cells (HEK293). It contains AA Gln 24 - Arg 152 (Accession # P36894-1).
• Expression System: HEK293
• Expression Region: Gln 24 - Arg 152
• Endotoxins: 1.0 EU per μg
• NCBI: CAA80257
• Storage: -20℃
• Buffer/Preservatives: 50 mM Tris, 100 mM Glycine, pH7.5
• Alternative names: BMPR-1A,ALK-3,ACVRLK3,CD292,SKR5
• Note: For research use only
• Application notes: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 40.3 kDa. The protein migrates as 56 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human BMPR-IA protein