Human B7-H5 / Gi24 / VISTA Protein

• Catalog Number: orb257209
• Category: Proteins
• Description: Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.
• Reactivity: Human
• Tag: C-10×His
• Form/Appearance: Powder
• Purity: 90%
• Conjugation: Unconjugated
• MW: 20.0 kDa
• Target: B7-H5
• Protein Sequence: AAH20568
• Source: Human B7-H5, His Tag (orb257209) is expressed from human 293 cells (HEK293). It contains AA Phe 33 - Ala 194 (Accession # AAH20568).
• Expression System: HEK293
• Expression Region: Phe 33 - Ala 194
• Endotoxins: 1.0 EU per μg
• NCBI: AAH20568
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: B7-H5,SISP1,Gi24,VISTA
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 20.0 kDa. The protein migrates as 33-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human B7-H5 protein