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Catalog Number | orb257197 |
---|---|
Category | Proteins |
Description | Azurocidin (AZU1) is also known as Heparin-binding protein (HBP), Cationic antimicrobial protein CAP37, is a neutrophil granule-derived antibacterial and monocyte- and fibroblast-specific chemotactic glycoprotein. which belongs to the peptidase S1 family and elastase subfamily. AZU1 / HBP contains 1 peptidase S1 domain. AZU1 binds heparin. The cytotoxic action of AZU1 is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. AZU1 may play a role in mediating recruitment of monocytes in the second wave of inflammation. |
Reactivity | Human |
Tag | C-6×His |
Form/Appearance | Powder |
Purity | 95% |
Conjugation | Unconjugated |
MW | 25.0 kDa |
Target | Azurocidin |
Protein Sequence | AAH69495 |
Source | Human Azurocidin, His Tag (orb257197) is expressed from human 293 cells (HEK293). It contains AA Ile 27 - Pro 250 (Accession # AAH69495). |
Expression System | HEK293 |
Expression Region | Ile 27 - Pro 250 |
Endotoxins | 1.0 EU per μg |
NCBI | AAH69495 |
Storage | -20℃ |
Buffer/Preservatives | PBS, pH7.4 |
Alternative names | AZU1,Azurocidin,HBP,AZAMP,AZU,CAP37,HUMAZUR,NAZC Read more... |
Note | For research use only |
Application notes | This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 25.0 kDa. The protein migrates as 34-42 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Expiration Date | 6 months from date of receipt. |
SDS-PAGE analysis of Human Azurocidin protein
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