Human Axl Protein

• Catalog Number: orb257196
• Category: Proteins
• Description: AXL Receptor Tyrosine Kinase is also known as Tyrosine-protein kinase receptor UFO, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. AXL contains two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains and one protein kinase domain. AXL is highly expressed in metastatic colon tumors. AXL is activated by GAS6-binding and subsequent autophosphorylation. AXL is involved in signal transduction from the extracellular matrix into the cytoplasm by binding growth factors, and thus implicated in the stimulation of cell proliferation.
• Reactivity: Human
• Tag: C-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 46.6 kDa
• Target: Axl
• Protein Sequence: AAH32229
• Source: Human Axl, His Tag (orb257196) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Pro 449 (Accession # AAH32229).
• Expression System: HEK293
• Expression Region: Ala 26 - Pro 449
• Endotoxins: 1.0 EU per μg
• NCBI: AAH32229
• Storage: -20℃
• Buffer/Preservatives: PBS, pH7.4
• Alternative names: AXL,UFO
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 46.6 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human Axl protein