Human Angiopoietin-like 4 / ANGPTL4 (166-406) Protein

• Catalog Number: orb257187
• Category: Proteins
• Description: Angiopoietin-related protein 4 (ANGPTL4) is also known as Hepatic fibrinogen / angiopoietin - related protein (HFARP), ARP4, PGAR. ANGPTL4 contains one fibrinogen C-terminal domain. ANGPTL4 is a homooligomer , and the homooligomer undergoes proteolytic processing to release its carboxyl fibrinogen-like domain, which circulates as a monomer. The homooligomer unprocessed form is able to interact with the extracellular matrix. ANGPTL4 may act as a regulator of angiogenesis and modulate tumorigenesis. ANGPTL4 inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action.
• Reactivity: Human
• Tag: N-6×His
• Form/Appearance: Powder
• Purity: 95%
• Conjugation: Unconjugated
• MW: 27.9 kDa
• Target: Angiopoietin-like 4
• Protein Sequence: NP_647475.1
• Source: Human Angiopoietin-like 4 (166-406), His Tag (orb257187) is expressed from human 293 cells (HEK293). It contains AA Pro 166 - Ser 406 (Accession # Q9BY76-1).
• Expression System: HEK293
• Expression Region: Pro 166 - Ser 406
• Endotoxins: 1.0 EU per μg
• NCBI: NP_647475.1
• Storage: -20℃
• Buffer/Preservatives: 50 mM MOPS, 100 mM NaCl, pH7.2
• Alternative names: ANGPTL4,ANGPTL2,ARP4,FIAF,HFARP,NL2,PGAR,pp1158,An
• Note: For research use only
• Application notes: This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 31-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Expiration Date: 6 months from date of receipt.

SDS-PAGE analysis of Human Angiopoietin-like 4 protein