Homovanillyl alcohol

SKU: orb1297337

Description

Homovanillyl alcohol

Research Area

Cell Biology, Metabolism Research

Key Properties

• CAS Number: 2380-78-1
• MW: 168.19
• Purity: 99.74%
• Formula: C₉H₁₂O₃
• SMILES: COC1=C(O)C=CC(CCO)=C1
• Target: Drug Metabolite,TNF
• Solubility: DMSO:125 mg/mL (743.21 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (11.89 mM)

Bioactivity

• In Vitro:
  Structurally related compounds have been assayed for their ability to reduce homocysteine-induced monocyte adhesion as well a the cell surfacee expression of intercellular adhesion molecule-1 (ICAM-1) in EA.hy.926 cells. As well-known, amon the selected phenolic compounds, hydroxytyrosol, Homovanillyl alcohol, an the hydroxycinnamic acid derivatives caffeic and ferulic acid display high scavenging activities, while tyrosol and p-coumaric acid are poorly active. All o the tested compounds, approaching potential in vivo concentration , significantly reduce homocysteine-induced cell adhesion and ICAM-1 expression.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Disclaimer: For research use only

Alternative Names

TNF-α, DrugMetabolite, Drug Metabolite, Inhibitor, Homovanillyl alcohol, inhibit

Compound Identifiers

PubChem CID

16928