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Catalog Number | orb1704890 |
---|---|
Category | Small Molecules |
Description | HLI 373 |
CAS Number | 502137-98-6 |
Purity | 98% |
MW | 341.41 |
SMILES | O=C1N=C2C(C(=O)N1C)=C(NCCCN(C)C)C=3C=CC=CC3N2C |
Formula | C18H23N5O2 |
Biological Activity | HLI373 is an efficacious Hdm2 inhibitor. Hdm2 is an ubiquitin ligase (E3). HLI373 is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents [1]. HLI 373 also shows prominent antimalarial activity [2]. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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