H-Ras (Q61L) protein

• Catalog Number: orb533564
• Category: Proteins
• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation Q61L results in a decreased GTPase activity as well as increased GDP/GTP exchange. This mutant constitutively activates the Ras-signaling pathway. Protein preparation is 77% GDP-and 23% GTP-loaded, measured by HPLC.
• Clonality: Recombinant
• Form/Appearance: liquid (Supplied in 64 mM Tris-HCl pH 7.2, 10 mM MgCl 2and 5 mM DTE)
• Purity: > 90% (SDS-PAGE)
• MW: Theoretical MW: 21.3 kDa (189 amino acids)
• Source: E. coli
• Storage: store at -80 °C
• Note: For research use only
• Expiration Date: 6 months from date of receipt.