H-Ras (G12V) protein

• Catalog Number: orb533565
• Category: Proteins
• Description: Ras proteins are members of the superfamily of small GTP-binding proteins that function as molecular switches controlling a variety of signaling and transport pathways. H-Ras is one of the classic human Ras proteins (H-, N-, K-Ras4A, and K-Ras4B). The mutation G12V leads to elimination of the intrinsic GTPase activity. H-Ras (G12V) is effective in activation of PI3K and PKB, whereas N-Ras and K-Ras are more potent towards MAP kinase.
• Clonality: Recombinant
• Form/Appearance: liquid (Supplied in 64 mM Tris-HCl pH 7.2, 10 mM MgCl 2and 5 mM DTE)
• Purity: > 90% (SDS-PAGE)
• MW: Theoretical MW: 20.97 kDa (189 amino acids)
• Source: E. coli
• Storage: store at -80 °C
• Note: For research use only
• Expiration Date: 6 months from date of receipt.