H-89 free base

• Catalog Number: orb1089339
• Category: Small Molecules
• Description: H-89 is a specific adenylyl cyclase inhibitor (DDA) and a cyclic AMP-dependent protein kinase inhibitor. H-89 blocks the action of equine growth hormone on in vitro maturation of equine oocytes. H-89 decreases the gain of excitation-contraction coupling and attenuates calcium sparks in the absence of beta-adrenergic stimulation. H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A.
• CAS Number: [127243-85-0]
• MW: 446.3607
• SMILES: BrC1C([H])=C([H])C(=C([H])C=1[H])/C(/[H])=C(\[H])/C([H])([H])N([H])C([H])([H])C([H])([H])N([H])S(C1=C([H])C([H])=C([H])C2C([H])=NC([H])=C([H])C1=2)(=O)=O
• Formula: C₂₀H₂₀BRN₃O₂S
• Note: For research use only
• Expiration Date: 12 months from date of receipt.