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    GNMT Protein, Human, Recombinant (His)

    GNMT Protein, Human, Recombinant (His)

    Catalog Number: orb1961208

    DispatchUsually dispatched within 5-10 working days
    $ 2,527.00
    Catalog Numberorb1961208
    CategorySmall Molecules
    DescriptionGNMT Protein, Human, Recombinant (His)
    Purity98.00%
    MW33-37 KDa, reducing conditions
    Biological ActivityGlycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases.
    NoteFor research use only
    Expiration Date12 months from date of receipt.
    • Recombinant Human GNMT Protein, His Tag [orb1552301]

      ≥90% as determined by SDS-PAGE

      This protein contains the human GNMT(Met1-Asg294) was fused with the N-terminal His Tag and expressed in E. coli.

      100 μg, 50 μg
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