You have no items in your shopping cart.
You have no items in your shopping cart.
Catalog Number | orb1961208 |
---|---|
Category | Small Molecules |
Description | GNMT Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 33-37 KDa, reducing conditions |
Biological Activity | Glycine N-Methyltransferase (GNMT) is a tetrameric cytosolic protein. GNMT catalyzes the synthesis of N-methylglycine from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. It can affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine, playing an important role in maintaining normal AdoMet levels. GNMT is highly expressed in liver. As a major folate-binding protein, GNMT takes part in the detoxification pathway. Defects in GNMT are the cause of hypermethioninemia. the patients with this deficiency are mild hepatomegaly and chronic elevation of serum transaminases. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human GNMT(Met1-Asg294) was fused with the N-terminal His Tag and expressed in E. coli. |
Filter by Rating