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Catalog Number | orb150500 |
---|---|
Category | Antibodies |
Description | Mouse monoclonal to GluA1 (ATTO-594). Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration.. |
Species/Host | Mouse |
Clonality | Monoclonal |
Clone Number | S355-1 |
Tested applications | ICC, IHC, WB |
Reactivity | Human, Mouse, Rat |
Isotype | IgG1 |
Immunogen | Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1 |
Concentration | 1 mg/ml |
Dilution range | WB (1:1000), ICC/IF (1:100) |
Conjugation | ATTO-594 |
MW | 100kDa |
Target | GluR1 |
Entrez | 50592 |
UniProt ID | P19490 |
NCBI | NP_113796 |
Storage | Conjugated antibodies should be stored at 4°C |
Buffer/Preservatives | PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated |
Alternative names | AMPA 1 antibody, AMPA selective glutamate receptor Read more... |
Note | For research use only |
Application notes | 1 µg/ml of SMC-440 was sufficient for detection of GluA1/GluR1 in 20 µg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody. |
Expiration Date | 12 months from date of receipt. |
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