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Catalog Number | orb1959865 |
---|---|
Category | Small Molecules |
Description | GFRAL/GFR alpha-like Protein, Human, Recombinant (His & Avi), Biotinylated |
Purity | 98.00% |
MW | The protein has a predicted MW of 40.7 kDa. Due to glycosylation, the protein migrates to 48-62 kDa based on Tris-Bis PAGE result. |
Biological Activity | GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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