Ganoderic acid A

• Catalog Number: orb1300229
• Category: Small Molecules
• Description: Ganoderic acid A
• CAS Number: 81907-62-2
• Purity: 99.55%
• MW: 516.67
• SMILES: C[C@]12C3=C([C@]4(C)[C@@](C[C@@H]3O)(C(C)(C)C(=O)CC4)[H])C(=O)C[C@]1(C)[C@@]([C@@H](CC(C[C@H](C(O)=O)C)=O)C)(C[C@@H]2O)[H]
• Formula: C₃₀H₄₄O₇
• Biological Activity: 1. Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1. 2. Ganoderic acid A can induce proliferation inhibition, apoptosis and suppression of invasion in human osteosarcoma HOS and MG-63 cells. 3. Ganoderic acid A promotes cisplatin-induced cell death by enhancing the sensitivity of HepG2 cells to cisplatin mainly via the signal transducer and activator of transcription 3 suppression, significantly suppresses IL-6-induced signal transducer and activator of transcription 3 phosphorylation.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.