Ganoderic acid A

SKU: orb1300229

Description

Ganoderic acid A is a bioactive triterpenoid that inhibits NF-κB and AP-1, demonstrating antitumor effects. It induces apoptosis and inhibits proliferation and invasion in osteosarcoma cells (HOS, MG-63) and enhances cisplatin sensitivity in HepG2 cells via STAT3 suppression. This compound is a valuable tool for cancer research in both in vitro and in vivo models.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 81907-62-2
• MW: 516.67
• Purity: 99.84% (May vary between batches)
• Formula: C₃₀H₄₄O₇
• SMILES: C[C@H](CC(=O)C[C@@H](C)C(O)=O)[C@H]1C[C@H](O)[C@@]2(C)C3=C(C(=O)C[C@]12C)[C@@]1(C)CCC(=O)C(C)(C)C1C[C@@H]3O
• Target: Endogenous Metabolite,Autophagy,NF-κB,Apoptosis
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (19.35 mM);DMSO:82.5 mg/mL (159.68 mM)

Storage & Handling

• Storage: keep away from direct sunlight,keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Endogenous Metabolite, Apoptosis, Autophagy, EndogenousMetabolite, Ganoderic acid A, NFkB, NFκB, NF-κB, NF-kB, Inhibitor, inhibit

Compound Identifiers

PubChem CID

73554535