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Catalog Number | orb1959196 |
---|---|
Category | Small Molecules |
Description | GALNT7 Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 73.6 kDa (predicted) |
Biological Activity | GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. GALNT7 acts as a glycosyltransferase in protein O-glycosylation, involving in the occurrence and development of CRC. GALNT7 silencing significantly attenuated the proliferation, clonogenicity and migration of LSCC cells and induced their cycling arrest. miR-30e may function as tumor suppressors in cervical cancer through downregulation of GALNT7. Both miR-30e and its novel target, GALNT7, may play an important role in the process of cervical cancer. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human GALNT7(Pro30-Val657) was fused with the C-terminal His Tag and expressed in Mammalian cells. |
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