Galectin 9 Antibody

• Catalog Number: orb2806646
• Category: Antibodies
• Description: Galectin 9 Antibody
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 1G3
• Tested applications: Blocking, ELISA, FA, IHC, NeA, WB
• Reactivity: Human, Mouse
• Isotype: IgG1
• Immunogen: The original antibody was generated by immunizing BALB/c mice with a recombinant c-terminus galectin-9 (residues 191 to 355 of the galectin-9 long isoform).
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: Galectin 9
• UniProt ID: O00182
• Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: Galectin-9; Gal-9; LGALS9; Ecalectin; Tumor antige
• Note: For research use only
• Application notes: The binding and binding specificity of the original format of this antibody to c-terminus Gal-9 were assessed via ELISA. Epitope mapping was also done using ELISA. Furthermore, this antibody was successfully used in WB and IHC assays (Barjon et al., 2012; PMID: 22805533). An scFv-CAR version of this antibody with therapeutic potential was developed and described (US20230295564A1). This antibody was successfully used to neutralize LGALS9 in a study focused on pancreatic neoplastic lesions (Quilbe et al., 2023; PMID: 38098486). This antibody was used in a T lymphocyte proliferation assay, specifically in assessing the immunomodulatory properties of extracellular vesicles (C15SEVs) derived from nasopharyngeal carcinoma and recombinant Galectin-9S. In this assay, the antibody was used to block the impact of C15SEVs and recombinant Galectin-9 on peripheral blood mononuclear cells (Lefebvre et al., 2023; PMID: 38117000).
• Expiration Date: 12 months from date of receipt.