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Catalog Number | orb1960073 |
---|---|
Category | Proteins |
Description | Human Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). |
Tag | N-His |
Purity | > 95% |
MW | 27.1 kDa (predicted). Due to glycosylation, the protein migrates to 35-45 kDa based on Tris-Bis PAGE result. |
UniProt ID | P17931 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | Human Galectin-3, also known as Mac-2, L29, CBP35, and epsilon BP, is classified as a chimeric member of the Galectin superfamily and contains one carbohydrate recognition domain (CRD) linked to a nonlectin domain.Galactose-specific lectin which binds IgE. May mediate with the alpha-3, beta-1 integrin the stimulation by CSPG4 of endothelial cells migration. Together with DMBT1, required for terminal differentiation of columnar epithelial cells during early embryogenesis (By similarity). |
Expression Region | Ala2-Ile250 |
Storage | -20°C |
Note | For research use only |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expiration Date | 6 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human LGALS3(Met1-Ile250) was fused with the C-terminal His Tag and expressed in E. coli. |
≥90% as determined by SDS-PAGE | |
This protein contains the human LGALS3(Ala2-Ile250) was fused with the N-terminal His Tag and expressed in E. coli. |