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Catalog Number | orb1956055 |
---|---|
Category | Small Molecules |
Description | GALE Protein, Human, Recombinant (His) |
Purity | 98.00% |
MW | 59.4 kDa (predicted) |
Biological Activity | UDP galactose-4'-epimerase, also known as GALE, enables the body to process a simple sugar called galactose, which is present in small amounts in many foods. Galactose is primarily part of a larger sugar called lactose, which is found in all dairy products and many baby formulas. UDP galactose-4'-epimerase catalyzes two distinct but analogous reactions: the epimerization of UDP-glucose to UDP-galactose, and the epimerization of UDP-N-acetylglucosamine to UDP-N-acetylgalactosamine. Defects in GALE causes epimerase-deficiency galactosemia (EDG), also known as galactosemia type 3. Clinical features include early-onset cataracts, liver damage, deafness and mental retardation. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
≥90% as determined by SDS-PAGE | |
This protein contains the human GALE(Met1-Ala348) was fused with the N-terminal His Tag and expressed in E. coli. |
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