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Forsythoside A

SKU: orb1223979

Description

Forsythoside A has anticomplementary, antimicrobial, antiinflammatory and antiendotoxin activities. Forsythoside A inhibits Infected cells was confirmed by infecting primary chicken embryo kidney cells.

Images & Validation

Key Properties

CAS Number79916-77-1
MW624.59
Purity>98% (HPLC)
FormulaC29H36O15
SMILESC[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OCCC3=CC(=C(C=C3)O)O)O)O)OC(=O)/C=C/C4=CC(=C(C=C4)O)O)O)O)O
TargetOthers
SolubilityPyridine, Methanol, Ethanol

Bioactivity

In Vitro
Forsythiaside A inhibits COX-2 at 30 μM, with inhibitory rate of 72%. Forsythiaside A (80 μM; 30 min) increases the contents of endogenous 2-AG, via decreasing MAGL expressions in Aβ25-35 (5 μM; 2 h) treated organotypic hippoc ampal slice. Forsythiaside A prevents Aβ25-35-induced neuro inflammation in a CB1R-dependent manner. Forsythiaside A (2.5-10 μg/mL; 12 h) inhibits Nrf2 signaling pathway in lung epithelial cells.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information

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5 mg
$ 80.00
10 mg
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25 mg
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50 mg
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100 mg
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500 mg
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