FM-381

• Catalog Number: orb507435
• Category: Small Molecules
• Description: FM-381 is a JAK3 specific reversible covalent inhibitor with IC50 of 127 pM for JAK3 and demonstrates 400-, 2,700- and 3,600-fold selectivity over JAK1, JAK2, and TYK2, respectively.
• CAS Number: [2226521-65-7]
• MW: 428.496
• SMILES: CN(C)C(=O)/C(=C/C1=CC=C(O1)C2=NC3=CN=C4C(=C3N2C5CCCCC5)C=CN4)/C#N
• Formula: C₂₄H₂₄N₆O₂
• Note: For research use only
• Expiration Date: 12 months from date of receipt.