FLT3 (C) Antibody, Rabbit Polyclonal

• Catalog Number: orb66757
• Category: Antibodies
• Description: Rabbit polyclonal to FLT3.FMS-related tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that regulates hematopoiesis.Upon ligand binding, the receptor is activated inducing a homodimer formation in the plasmamembrane leading to autophosphorylation of the receptor. Activated FLT3 can also phosphorylateand activate multiple cytoplasmic effector molecules in pathways implicated in apoptosis, proliferationand differentiation of hematopoietic cells in bone marrow. Mutations that result in constitutiveactivation of this receptor are associated with acute myeloid leukemia and acute lymphoblasticleukemia.
• Clonality: Polyclonal
• Species/Host: Rabbit
• Conjugation: Unconjugated
• Reactivity: Human, Mouse
• Buffer/Preservatives: 0.01% NaN3
• Purity: Affinity purification
• Immunogen: C-terminal region of mouse FLT3
• UniProt ID: Q00342
• MW: 113
• Tested applications: WB
• Dilution range: WB:1:1000-1:5000
• Storage: -20°C
• Alternative names: anti-FLT3 antibody,anti-B230315G04 antibody,anti-C
• Note: For research use only

Western blot analysis of total cell extracts from human K562 using FLT3 antibody