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Catalog Number | orb1304037 |
---|---|
Category | Small Molecules |
Description | FIPI |
CAS Number | 939055-18-2 |
Purity | 99.08% |
MW | 421.47 |
SMILES | O=C1N(C=2C(N1)=CC=CC2)C3CCN(CCNC(=O)C=4NC=5C(C4)=CC(F)=CC5)CC3 |
Formula | C23H24FN5O2 |
Biological Activity | FIPI (5-Fluoro-2-indolyl deschlorohalopemide) is a derivative of halopemide which potently inhibits both PLD1 (IC50 = 25 nM) and PLD2 (IC50 = 20 nM); prevents PLD regulation of F-actin cytoskeleton reorganization, cell spreading, and chemotaxis. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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