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Catalog Number | orb1961112 |
---|---|
Category | Proteins |
Description | Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation. |
Tag | C-6xHis |
Purity | 98.00% |
MW | 65 KDa (reducing condition) |
UniProt ID | Q8N441 |
Protein Sequence | Ala25-Pro378 |
Expression System | HEK293 Cells |
Biological Origin | Human |
Biological Activity | Fibroblast Growth Factor Receptor-Like 1 (FGFRL1) is a single-pass type I membrane protein that belongs to the FGF receptor family. The mature human FGFRL1 consists of a 354 amino acid extracellular domain (ECD) with 3 Ig-like C2-type domains, a 21 amino acid transmembrane segment, and a 134 amino acid cytoplasmic domain. FGFR1 expressed in various tissues, preferentially in cartilaginous tissues and pancreas. It highly expressed in the liver, kidney, heart, brain and skeletal muscle, weakly expressed in the lung, small intestine and spleen. FGFRL1 has a negative effect on cell proliferation. |
Expression Region | Ala25-Pro378 |
Storage | -20°C |
Note | For research use only |
Application notes | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Expiration Date | 6 months from date of receipt. |
> 92% by SDS-PAGE. | |
Recombinant Human FGF R5/FGFRL1 Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Ala 25 - Pro 378 ) of human FGF R5/FGFRL1 (Accession #NP_068742.2) fused with a 6��His Tag at the C-terminus. |