FcRn Antibody

• Catalog Number: orb1821541
• Category: Antibodies
• Description: FcRn Antibody
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: h22-0015
• Tested applications: Blocking, In vitro, In vivo
• Reactivity: Human
• Isotype: IgG
• Immunogen: The original antibody was generated by immunizing Balb/c mice with recombinant FcRn.
• Concentration: 1 mg/ml
• Conjugation: Unconjugated
• Target: FcRn
• UniProt ID: P55899
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: IgG receptor FcRn large subunit p51; FCGRT; IgG Fc
• Note: For research use only
• Application notes: The antibody was employed in blocking experiments with HEK293 cells that overexpress FcRn. The results showed that the antibody has a good effect of blocking the binding of IgG to FcRn at the cellular level (IC50: 11.4nM). The effect of the antibody was tested in human FcRn transgenic mice. The antibody was able to increase IgG catabolism in vivo by blocking FcRn binding (CN113484526).
• Expiration Date: 12 months from date of receipt.