Fc gamma R III antibody

• Catalog Number: orb613918
• Category: Antibodies
• Description: Mouse monoclonal antibody to Fc gamma R III
• Species/Host: Mouse
• Clonality: Monoclonal
• Clone Number: 3G8
• Tested applications: Blocking, FC, IHC, IP
• Reactivity: Human, Marmoset, Primate
• Isotype: IgG1
• Immunogen: 3G8 was prepared by immunizing mice with human PMN (polymorphonuclear leukocytes) cells.
• Concentration: 1 mg/ml
• Purity: Purified
• Conjugation: Unconjugated
• Target: Fc gamma receptor III
• UniProt ID: Q9ULV2
• Storage: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.
• Buffer/Preservatives: PBS with 0.02% Proclin 300.
• Alternative names: CD16; low affinity IgG receptor III; FcγRIII; low
• Note: For research use only
• Application notes: 3G8 antibody was used to construct a recombinant bispecific scFv (bsscFv) along with the mAb clone F3.3 anti-HLA class II antibody (connected by a (Gly4Ser)4 linker)which was expressed in SF21 insect cells. This bsscFv allows NK cells to target malignant B lymphoid cells and mediates effector cell lysis (ASCC) of the malignant cells (also lysis of primary leukaemia samples). 3G8 is also able to block neutrophil phagocytosis and stimulates NK cell proliferation, and can be used in FC, SPR, IP and IHC studies.
• Expiration Date: 12 months from date of receipt.